Publications 成果・実績


櫻井チーム / Sakurai Team

  1. Nagahide Takahashi, Takeshi Sakurai, Ozlem Bozdagi-Gunal, Nathan P. Dorr, Joanne Moy, Lisa Krug, Miguel Gama-Sosa, Gregory A. Elder, Rick J. Koch, Ruth H. Walker, Patrick, R. Hof, Kenneth L. Davis, and Joseph D. Buxbaum.
    Increased expression of receptor phosphotyrosine phosphatase-ß/, is associated with molecular, cellular, behavioral and cognitive schizophrenic phenotypes.
    Translational Psychiatry, 1, e8, 1-10, 2011


    http://www.nature.com/tp/journal/v1/n5/abs/tp20118a.html

  2. Nagahide Takahashi, Karin S. Nielsen, Branko Aleksic, Steffen Peterson, Masashi Ikeda, Itaru Kushima, Nathalie Vacaresse, Hiroshi Ujike, Nakao Iwata, Venonique Debreuil, Naheed Mirza, Takeshi Sakurai, Norio Ozaki, Joseph D. Buxbaum, and Jan Sap.
    Loss of function studies in mice and genetic association link protein tyrosine phosphatase α to schizophrenia.
    Biol. Psychiatry, 70, 626-635, 2011

  3. Takaaki Kuwajima, Yutaka Yoshida, Noriko Takegahara, Timothy J. Petros, Atsushi Kumanogoh, Thomas M. Jessell, Takeshi Sakurai, and Carol A. Mason.
    Optic chiasm presentation of Semaphorin6D in context with Plexin-A1 and Nr-CAM promotes retinal axon crossing.
    Neuron, 74, 676-690, 2012


    http://www.ncbi.nlm.nih.gov/pubmed/22632726


総説 / Review Article
  1. Nagahide Takahashi, Takeshi Sakurai, Kenneth Davis, and Joseph D. Buxbaum.
    Linking oligodendrocyte and myelin dysfunction to neurocircuitry abnormalities in schizophrenia.
    Prog. Neurobiol., 93, 13-22, 2010


    http://www.ncbi.nlm.nih.gov/pubmed/20950668

  2. Takeshi Sakurai.
    The role of NrCAM in neural development and disorders -beyond a simple glue in the brain-Mol. Cell. Neurosci., 49, 351-363, 2012


    http://www.ncbi.nlm.nih.gov/pubmed/22182708

  3. 櫻井武、澤明 編集
    心と体のクロストークから解く精神・神経疾患
    発症基盤・病態生理を担う分子カスケードから臨床応用まで
    実験医学増刊 Vol.30 No.13 2012年7月



疋田チーム / Hikita Team

  1. Takatoshi Hikida, Hanna Jaaro-Peled, Saurav Seshadri, Kenichi Oishi, Caroline Hookway, Stephanie Kong, Di Wu, Rong Xue, Manuella Andradé, Stephanie Tankou, Susumu Mori, Michela Gallagher, Koko Ishizuka, Mikhail Pletnikov, Satoshi Kida, and Akira Sawa.
    Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans.
    Proc. Natl. Acad. Sci. U. S. A., 104, 14501-14506, 2007


    http://www.ncbi.nlm.nih.gov/pubmed/17675407

  2. Takatoshi Hikida, Kensuke Kimura, Norio Wada, Kazuo Funabiki, and Shigetada Nakanishi. Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behavior. Neuron, 66, 896-907, 2010


    http://www.ncbi.nlm.nih.gov/pubmed/20620875

  3. Yuichiro Hayashi, Yoshiaki Tagawa, Satoshi Yawata, Shigetada Nakanishi, and Kazuo Funabiki. Spatio-temporal control of neural activity in vivo using fluorescence microendoscopy. Eur. J. Neurosci., in press.


    http://www.ncbi.nlm.nih.gov/pubmed/22780218


総説 / Review Article
  1. Shigetada Nakanishi, Satoshi Kaneko, Takatoshi Hikida, Dai Watanabe, and Ira Pastan.
    Role of synaptic integration of dopaminergic and cholinergic transmissions in basal ganglia function.
    International Congress Series, 1250, 487-492, 2003


    http://www.sciencedirect.com/science/article/pii/S0531513103009828

  2. 疋田貴俊、神谷篤 精神疾患モデル動物の可能性 –遺伝子から神経回路へ-
    実験医学 2010年9月号 28, 2205-2210, 2010

  3. 疋田貴俊 精神疾患の分子遺伝学:最近の知見
    脳神経外科速報 21, 1250-1254, 2011



友田チーム / Tomoda Team

  1. Hirofumi Toda, Hiroaki Mochizuki, Rafael Flores III, Rebecca Josowitz, Tatiana B. Krasieva, Vickie J. LaMorte, Emiko Suzuki, Joseph G. Gindhart, Katsuo Furukubo-Tokunaga, and Toshifumi Tomoda.
    UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly.
    Genes Dev., 22, 3292-3307, 2008


    http://www.ncbi.nlm.nih.gov/pubmed/19056884

  2. Yogesh P. Wairkar, Hirofumi Toda, Hiroaki Mochizuki, Katsuo Furukubo-Tokunaga, Toshifumi Tomoda, and Aaron DiAntonio.
    Unc-51 controls active zone density and protein composition by downregulating ERK signaling.
    J Neurosci., 29, 517-528, 2009


    http://www.ncbi.nlm.nih.gov/pubmed/19144852

  3. Rafael Flores III, Yuki Hirota, Brian Armstrong, Akira Sawa, and Toshifumi Tomoda. DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway. Neurosci. Res., 71, 71-77, 2011.


総説 / Review Article
  1. David J. Solecki, Eve-Ellen Govek, Toshifumi Tomoda, and Mary E. Hatten.
    Neuronal polarity in CNS development.
    Genes Dev., 20, 2639-2647, 2006


    http://www.ncbi.nlm.nih.gov/pubmed/17015428

  2. 疋田貴俊、友田利文
    精神疾患モデル動物の作製と治療法スクリーニング
    実験医学増刊 2012年7月、30, 2074-2079, 20121