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​当教室にかかわる研究実績を紹介します（2020年12月現在）。

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  • Sakurai T, Shinobu L.A, Sawa A
    Schizophrenia research in 2013: Are we making progress?
    Neurobiol Dis. 2013; 53:1-2.

  • Ueda S, Niwa M, Hioki H, Sohn J, Kaneko T, Sawa A, Sakurai T
    Sequence of molecular events during maturation of developing mouse prefrontal cortex.
    Mol Neuropsychiatry. 2015; 1:94-104.

  • Sakurai T, Gamo N.J, Hikida T, Kim S.H, Murai T, Tomoda T, Sawa A
    Converging models of schizophrenia? Network alterations of prefrontal cortex underlying cognitive impairments?
    Prog Neurobiol. 2015; 134:178-201.

  • Gamo NJ, Birknow MR, Sullivan D, Kondo MA, Horiuchi Y, Sakurai T, Slusher BS, Sawa A
    Valley of death: A proposal to build a “translational bridge” for the next generation.
    Neurosci Res. 2017; 115:1-4.

  • Takayanagi Y, Ishizuka K, Laursen TM, Yukitake H, Yang K, Cascella NG, Ueda S, Sumitomo A, Narita Z, Horiuchi Y, Niwa M, Taguchi A, White MF, Eaton WW, Mortensen PB, Sakurai T, Sawa A.
    From population to neuron: exploring common mediators for metabolic problems and mental illnesses.
    Mol Psychiatry. 2020 Nov 10. doi: 10.1038/s41380-020-00939-5. Online ahead of print. PMID: 33173197

  • Sakurai T, Sawa A.
    Editorial for "What can clinical findings tell us about the neurobiology of schizophrenia?
    Neurobiol Dis. 2019 Nov; 131:104521. Epub 2019 Jul 9. PMID: 31299219 No abstract available.

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  • Hayashi Y, Sawa A, Hikida T
    Impaired hippocampal activity at the goal zone on the place preference task in a DISC1 mouse model.
    Neurosci Res. 2016; 106:70-73.

  • Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A, Hikida T
    Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCage.
    Learn Mem. 2016; 23:359-364.

  • Morita M, Wang Y, Sasaoka T, Okada K, Niwa M, Sawa A, Hikida T
    Dopamine D2L receptor is required for visual discrimination and reversal learning.
    Mol Neuropsychiatry. 2016; 2:124-132.

  • Hikida T, Morita M, Kuroiwa M, Macpherson T, Shuto T, Sotogaku N, Niwa M, Sawa A, Nishi A.
    Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice.
    Neurosci Res. 2020 Feb; 151:38-45. Epub 2019 Mar 1.

  • Hikida T, Yao S, Macpherson T, Fukakusa A, Morita M, Kimura H, Hirai K, Ando T, Toyoshiba H, Sawa A.
    Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex.
    Sci Rep. 2020 Feb 4;10(1):1838.

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  • Tomoda T, Sumitomo A, Jaaro-Peled H, Sawa A

　   Utility and validity of DISC1 mouse models in biological psychiatry.

　   Neurosci. 2016; 321:99-107.

  • Sumitomo A, Ueta K, Horike K, Mauchi S, Hirai K, Hikida T, Sakurai T, Sawa A, Tomoda T

　   Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits.

　   Neurosci Res. 2017; 117:54-61.

  • Sumitomo A, Saka A, Ueta K, Horike K, Hirai K, Gamo NJ, Hikida T, Nakayama KI, Sawa A, Sakurai T, Tomoda T

　   Methylphenidate and guanfacine ameliorate ADHD-like phenotypes in Fez1-deficient mice.

　   Mol Neuropsychiatry. 2018 May; 3(4)223-233.Epub 2018 Apr 26.

  • Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, Sakurai T, Ishizuka K, Sawa A, Tomoda T.
    Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons.
    Hum Mol Genet. 2018 Sep 15;27(18):3165-3176.

  • Sumitomo A, Horike K, Hirai K, Butcher N, Boot E, Sakurai T, Nucifora Jr F.C, Bassett A.S, Sawa A, Tomoda T.

　  A mouse model of 22q11.2 deletions: molecular and behavioral signatures of Parkinson’s disease and schizophrenia.

　  Sci Adv. 2018 Aug 15;4(8) eCollection 2018 Aug.

  • Tomoda T, Yang K, Sawa A.
    Neuronal Autophagy in Synaptic Functions and Psychiatric Disorders.

　  Biol Psychiatry. 2020 May 1;87(9):787-796. Epub 2019 Jul 29.　PMID: 31542152

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  • Shinohara R, Taniguchi M, Ehrlich AT, Yokogawa K, Deguchi Y, Cherasse Y, Lazarus M, Urade Y, Ogawa A, Kitaoka S,

      Sawa A, Narumiya S, Furuyashiki T

     Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial

　  prefrontal  cortex and contributes to suppression of stress susceptibility in mice.

     Mol Psychiatry. 2018 Aug;23(8):1717-1730. Epub 2017 Sep 19.

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  • Toritsuka M, Kimoto S, Muraki K, Landek-Salgado MA, Yoshida A, Yamamoto N, Horiuchi Y, Hiyama H,  Tajinda K, Keni N, Illingworth E, Iwamoto T, Kishimoto T, Sawa A, Tanigaki K

　  Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion 　　

　  syndrome mouse model.<br>Proc Natl Acad Sci U S A. 2013; 110(43):17552-7.

  • Toritsuka M, Kimoto S, Muraki K, Kitagawa M, Kishimoto T, Sawa A, Tanigaki K

　  Regulation of striatal dopamine responsiveness by Notch/RBP-J signaling.

　  Transl Psychiatry. 2017; 7(3):e1049.

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  • Yoshihara Y, Lisi G, Yahata N, Fujino J, Matsumoto Y, Miyata J, Sugihara G, Urayama S, Kubota M, Yamashita M, Hashimoto R, Ichikawa N, Cahn W, van Haren NEM, Mori S, Okamoto Y, Kasai K, Kato N, Imamizu H, Kahn RS, Sawa A, Kawato M, Murai T, Morimoto J, Takahashi H
    Overlapping but asymmetrical relationships between schizophrenia and autism revealed by brain connectivity
    Schizophr Bull. 2020 Apr 17;46(5):1210-1218. Online ahead of print.

  • Miyata J, Winton-Brown T, Sedlak T, Aso T, Cascella N, Coughlin J, Crossley N, Düzel E, Howell C, Isobe M, Kochiyama T, Mori S, Mori Y, Murai T, Nucifora F, Sakai Y, Sawamoto N, Urayama S, Watkins C, Takahashi H, Sawa A, McGuire P.   
    Connectivity between two salience-associated networks in the human brain and their abnormalities at different stages of psychosis.
    [Submitted].

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